Minimal structural and glycosylation requirements for ST6Gal I activity and trafficking

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چکیده

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Minimal structural and glycosylation requirements for ST6Gal I activity and trafficking.

The influence of N-linked glycosylation on the activity and trafficking of membrane associated and soluble forms of the STtyr isoform of the ST6Gal I has been evaluated. We have demonstrated that the enzyme is glycosylated on Asn 146 and Asn 158 and that glycosylation is not required for the endoplasmic reticulum to Golgi transport of the membrane-associated form of the STtyr isoform. In additi...

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ژورنال

عنوان ژورنال: Glycobiology

سال: 2000

ISSN: 0959-6658,1460-2423

DOI: 10.1093/glycob/10.5.531